Histological results shows new collagen and elastin following IntraGen non-invasive treatments using Grid Fractional RF technology for uniform energy infusion and real-time dermal monitoring for pain-free no downtime treatments.

From Ma Christina Tanciangco-Javier,M.D. , Novel Dermatology and Cosmetic Surgicenter, Philippines

[IntraGen] The clinical and histological effects of a new 6MHz Monopolar RF Device for facial skin tightening (by Dr Ma Christina Tanciangco-Javier)

H&E Stain at 40x of biopsy specimen before and immediately after 2 pulses using the GFR  71j/cm2 showing contraction of the dermis immediately post-RF with no signs of epidermal injury.

 

[IntraGen] The clinical and histological effects of a new 6MHz Monopolar RF Device for facial skin tightening (by Dr Ma Christina Tanciangco-Javier)2

H & E Staining at 100xMagnification . Comparison of biopsy specimens before, 3 months after and 6 months after treatment showing more compactly arranged collagen bundles at 3 months and thicker collagen bundles at 6 months post treatment.

 

 

Following from Gayoung Lee, MD of Kangbuk Samsung Medical Center

H&E stain showing neocollagenesis and neoelastogenesis
intragen_HE stain bsaeline  intragen he stain 70 days
Baseline and 70  post IntraGen treatment

 

Elastic Van Gieson stain showing neoelastogenesis
intragen elastic va gieson baseline  intragen elsastic 70 days
Baseline and 70  post IntraGen treatment

 

Masson’s trichrome stain showing neocollagenesis
intragen massons trichome  intragen massons 70 day
Baseline and 70  post IntraGen treatment